Tyvaso

Adult Dosing .

Dosage forms:  NEB: 1.74 mg per 2.9 mL

Special Note

[strength clarification]

Info: 6 mcg treprostinil = 1 breath; doses expressed as treprostinil amount

pulmonary arterial HTN

[54-72 mcg NEB qid]

Start: 18 mcg NEB qid, incr. by 18 mcg/dose q1-2wk; Info: space doses 4h apart; if initial dose not tolerated, decr. dose to 6 mcg or 12 mcg NEB qid, then may subsequently incr. to target dose

pulmonary HTN, interstitial lung dz-associated

[54-72 mcg NEB qid]

Start: 18 mcg NEB qid, incr. by 18 mcg/dose q1-2wk; Info: space doses 4h apart; if initial dose not tolerated, decr. dose to 6 mcg or 12 mcg NEB qid, then may subsequently incr. to target dose

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised; Info: titrate slowly

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.