Stelara

Adult Dosing .

Dosage forms:  INJ (pre-filled syringe): 45 mg per 0.5 mL, 90 mg per mL; INJ (vial, SC): 45 mg per 0.5 mL; INJ (vial, IV): various

psoriasis, moderate-severe plaque

[<100 kg]

Dose: 45 mg SC q12wk; Start: 45 mg SC x1 on wk 0, 4, then q12wk

[>100 kg]

Dose: 90 mg SC q12wk; Start: 90 mg SC x1 on wk 0, 4, then q12wk; Info: may decr. dose to 45 mg if full dose intolerable

psoriatic arthritis

[45 mg SC q12wk]

Start: 45 mg SC x1 on wk 0, 4, then q12wk; Info: give 90 mg SC x1 on wk 0, 4, then q12wk if >100 kg w/ coexisting plaque psoriasis

Crohn dz, moderate-severe

[induction tx, <55kg]

Dose: 260 mg IV x1

[induction tx, 55-85kg]

Dose: 390 mg IV x1

[induction tx, >85kg]

Dose: 520 mg IV x1

[maintenance tx]

Dose: 90 mg SC q8wk; Start: 8wk after induction dose

ulcerative colitis, moderate-severe

[induction tx, <55kg]

Dose: 260 mg IV x1

[induction tx, 55-85kg]

Dose: 390 mg IV x1

[induction tx, >85kg]

Dose: 520 mg IV x1

[maintenance tx]

Dose: 90 mg SC q8wk; Start: 8wk after induction dose

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ (pre-filled syringe): 45 mg per 0.5 mL, 90 mg per mL; INJ (vial, SC): 45 mg per 0.5 mL; INJ (vial, IV): various

psoriasis, moderate-severe plaque

[6 yo and older, <60 kg]

Dose: 0.75 mg/kg/dose SC q12wk; Start: 0.75 mg/kg/dose SC x1 on wk 0, 4, then q12wk

[6 yo and older, 60-100 kg]

Dose: 45 mg SC q12wk; Start: 45 mg SC x1 on wk 0, 4, then q12wk

[6 yo and older, >100 kg]

Dose: 90 mg SC q12wk; Start: 90 mg SC x1 on wk 0, 4, then q12wk

psoriatic arthritis

[6 yo and older, <60 kg]

Dose: 0.75 mg/kg/dose SC q12wk; Start: 0.75 mg/kg/dose SC x1 on wk 0, 4, then q12wk

[6 yo and older, >60 kg]

Dose: 45 mg SC q12wk; Start: 45 mg SC x1 on wk 0, 4, then q12wk; Info: give 90 mg SC x1 on wk 0, 4, then q12wk if >100 kg w/ coexisting plaque psoriasis

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]