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Intuniv
guanfacine
Adult Dosing .
Adult dosing is currently unavailable or not applicable for this drug.
Peds Dosing .
- Dosage forms: ER TAB: 1 mg, 2 mg, 3 mg, 4 mg
Special Note
- [formulation clarification]
- Info: not interchangeable w/ guanfacine IR products; do not substitute on a mg to mg basis; retitrate if switching from IR to ER product
ADHD
- [6-17 yo, 25-33.9 kg]
- Dose: 2-3 mg PO qd; Start: 1 mg PO qd, incr. by 1 mg/day qwk; Alt: 0.05-0.12 mg/kg/dose PO qd; Info: for monotherapy or adjunct tx; do not give w/ high fat meals; do not cut/crush/chew tab; taper dose by 1 mg/day q3-7 days to D/C
- [6-17 yo, 34-41.4 kg]
- Dose: 2-4 mg PO qd; Start: 1 mg PO qd, incr. by 1 mg/day qwk; Alt: 0.05-0.12 mg/kg/dose PO qd; Info: for monotherapy or adjunct tx; do not give w/ high fat meals; do not cut/crush/chew tab; taper dose by 1 mg/day q3-7 days to D/C
- [6-17 yo, 41.5-49.4 kg]
- Dose: 3-5 mg PO qd; Start: 1 mg PO qd, incr. by 1 mg/day qwk; Alt: 0.05-0.12 mg/kg/dose PO qd; Info: for monotherapy or adjunct tx; do not give w/ high fat meals; do not cut/crush/chew tab; taper dose by 1 mg/day q3-7 days to D/C
- [6-17 yo, 49.5-58.4 kg]
- Dose: 3-6 mg PO qd; Start: 1 mg PO qd, incr. by 1 mg/day qwk; Alt: 0.05-0.12 mg/kg/dose PO qd; Info: for monotherapy or adjunct tx; do not give w/ high fat meals; do not cut/crush/chew tab; taper dose by 1 mg/day q3-7 days to D/C
- [6-17 yo, 58.5-91 kg]
- Dose: 4-7 mg PO qd; Start: 1 mg PO qd, incr. by 1 mg/day qwk; Alt: 0.05-0.12 mg/kg/dose PO qd; Info: for monotherapy or adjunct tx; do not give w/ high fat meals; do not cut/crush/chew tab; taper dose by 1 mg/day q3-7 days to D/C
- [6-17 yo, >91 kg]
- Dose: 5-7 mg PO qd; Start: 1 mg PO qd, incr. by 1 mg/day qwk; Alt: 0.05-0.12 mg/kg/dose PO qd; Info: for monotherapy or adjunct tx; do not give w/ high fat meals; do not cut/crush/chew tab; taper dose by 1 mg/day q3-7 days to D/C
renal dosing
- [see below]
- renal impairment: not defined; Info: consider decr. usual dose if significant impairment
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined; Info: consider decr. usual dose if significant impairment