Menveo

Adult Dosing .

Dosage forms:  INJ

invasive meningococcal dz prevention

[18-55 yo, pts w/ low infection risk]

Dose: 0.5 mL IM x1; Info: for military recruits, college students living in residential housing not previously vaccinated at 16 yo or older, lab workers exposed to N. meningitidis, or travelers to hyperendemic or epidemic areas; give booster q5y if continued risk in lab workers and travelers; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[18-55 yo, pts w/ high infection risk]

Dose: 0.5 mL IM x2 doses at least 2mo apart; Info: for pts w/ asplenia, HIV infection, persistent complement component deficiency, or pts on complement inhibitor tx; give booster q5y if continued risk; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[56 yo and older, pts w/ low infection risk (off-label)]

Dose: 0.5 mL IM x1; Info: for lab workers exposed to N. meningitidis or travelers to hyperendemic or epidemic areas; give booster q5y if continued risk; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

[56 yo and older, pts w/ high infection risk (off-label)]

Dose: 0.5 mL IM x2 doses at least 2mo apart; Info: for pts w/ asplenia, HIV infection, persistent complement component deficiency, or pts on complement inhibitor tx; give booster q5y if continued risk; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

Special Note

[formulation clarification]

Info: gray and orange cap vials for use in pts 2 mo and older; pink vial for use in pts 10 yo and older

invasive meningococcal dz prevention

[routine vaccination]

Dose: 0.5 mL IM x1 at 11-12 yo, then 0.5 mL IM x1 at 16 yo; Info: if 1st dose given at 13-15 yo, give booster at 16-18 yo; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[non-routine vaccination, 2 mo at series start]

Dose: 0.5 mL IM x1 at 2 mo, 4 mo, 6 mo, and 12 mo for 4 total doses; Info: for pts w/ asplenia, sickle cell dz, HIV infection, persistent complement component deficiency, on complement inhibitor tx, or travelers to hyperendemic or epidemic areas; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[non-routine vaccination, 3-6 mo at series start (off-label)]

Dose: 0.5 mL IM x3 doses at least 8wk apart, then 0.5 mL IM x1 dose at 12 mo or older and at least 12wk after prior dose; Info: for pts w/ asplenia, sickle cell dz, HIV infection, persistent complement component deficiency, on complement inhibitor tx, or travelers to hyperendemic or epidemic areas; 3rd dose not needed if 2nd dose given after 7 mo; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[non-routine vaccination, 7-23 mo at series start]

Dose: 0.5 mL IM x2 doses at least 3mo apart; Info: for pts w/ asplenia, sickle cell dz, HIV infection, persistent complement component deficiency, on complement inhibitor tx, or travelers to hyperendemic or epidemic areas; give 2nd dose when pt 1 yo and older; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[non-routine vaccination, 2-6 yo, pts w/ low infection risk]

Dose: 0.5 mL IM x1; Info: for travelers to hyperendemic or epidemic areas; give booster 3y after last dose, then q5y if continued risk; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[non-routine vaccination, 2-6 yo, pts w/ high infection risk]

Dose: 0.5 mL IM x2 doses at least 8wk apart; Info: for pts w/ persistent complement component deficiency, complement inhibitor tx, asplenia, sickle cell dz, or HIV infection; give booster 3y after last dose, then q5y if continued risk; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[non-routine vaccination, 7 yo and older, pts w/ low infection risk]

Dose: 0.5 mL IM x1; Info: for military recruits, college students living in residential housing not previously vaccinated at 16 yo or older, or travelers to hyperendemic or epidemic areas; give booster q5y if continued risk; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[non-routine vaccination, 7 yo and older, pts w/ high infection risk]

Dose: 0.5 mL IM x2 doses at least 8wk apart; Info: for pts w/ persistent complement component deficiency, complement inhibitor tx, asplenia, sickle cell dz, or HIV infection; give booster q5y if continued risk; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]