Select a medication above to begin.
Lumizyme
alglucosidase alfa
Black Box Warnings .
Hypersensitivity Rxn
life-threatening rxns incl. anaphylaxis have occurred; anaphylaxis has occurred during early tx and after extended tx duration; admin. where appropriate medical support incl. cardiopulmonary resuscitation equip. available; D/C immediately and start appropriate tx if severe rxn occurs; counsel pts on s/sx and to seek immediate medical attention if they occur at any time
Immune-Mediated Rxn
rxns presenting as proteinuria, nephrotic syndrome, and necrotizing skin lesions have occurred; monitor for systemic rxns involving skin and other organs during tx
Cardiorespiratory Failure Risk
perform additional monitoring in infantile-onset Pompe dz pts w/ compromised cardiac or resp. fxn; risk of serious exacerbation of compromised cardiac or resp. fxn due to fluid overload
Adult Dosing .
Dosage forms: INJ
Pompe dz
- [20 mg/kg/dose IV q2wk]
- Info: consider premed w/ antipyretic, antihistamine, corticosteroids
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Pompe dz
- [20 mg/kg/dose IV q2wk]
- Info: consider premed w/ antipyretic, antihistamine, corticosteroids
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]