Select a medication above to begin.
Aldurazyme
laronidase
Black Box Warnings .
Hypersensitivity Rxn
life-threatening rxns incl. anaphylaxis have occurred; admin. where appropriate medical support incl. cardiopulmonary resuscitation equip. available; D/C immediately and start appropriate tx if severe rxn occurs; may consider desensitization procedure in pts w/ severe rxn
Acute Respiratory Complication Risk
pts w/ compromised resp. fxn or acute resp. dz may be at risk of serious acute exacerbations of their resp. compromise from infusion rxns; perform additional monitoring in these pts
Adult Dosing .
Dosage forms: INJ
mucopolysaccharidosis I
- [0.58 mg/kg/dose IV qwk]
- Info: for pts w/ Hurler, Hurler-Scheie, and moderate-severe Scheie forms; consider premed w/ antihistamine +/- antipyretic
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
mucopolysaccharidosis I
- [6 mo and older]
- Dose: 0.58 mg/kg/dose IV qwk; Info: for pts w/ Hurler, Hurler-Scheie, and moderate-severe Scheie forms; consider premed w/ antihistamine +/- antipyretic
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]