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Nature-Throid
thyroid (porcine)
Black Box Warnings .
Not for Obesity/Weight Loss
not for obesity/weight loss alone or as combo tx; in euthyroid pts doses within range of daily hormonal requirements ineffective for weight loss; larger doses may cause serious or life-threatening toxicity, especially given in combo w/ sympathomimetic amines incl. those w/ anorectic effects
Adult Dosing .
Dosage forms: TAB: 16.25 mg, 32.5 mg, 48.75 mg, 65 mg, 81.25 mg, 97.5 mg, 113.75 mg, 130 mg, 146.25 mg, 162.5 mg, 195 mg, 260 mg, 325 mg
Currently Unavailable in US
- [estimated availability unknown]
Special Note
- [strength clarification]
- Info: thyroid (porcine) contains liothyronine (T3) and levothyroxine (T4) in approx. 1:4 ratio; 60-65 mg thyroid (porcine) contain 9 mcg T3 and 38 mcg T4
- [thyroid product equivalencies]
- Info: for product conversion purposes, 60-65 mg thyroid (porcine) = 100 mcg levothyroxine = 25 mcg liothyronine = 1 grain liotrix
hypothyroidism
- [65-130 mg PO qd]
- Start: 32.5 mg PO qd, incr. 16.25 mg/day q6wk; Info: use lower start dose, slower titration if elderly, long-standing dz, myxedema, or cardiac dz/risk factors; may start full replacement dose for healthy pts <65 yo w/o cardiac dz; suspect malabsorption, drug interaction, or noncompliance if failed response to 195 mg/day
thyroid suppression test
- [2.5 mg/kg/dose PO qd x7-10 days]
- Info: check radioactive iodine uptake pre- and post-tx, >50% suppression of uptake = normal
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: TAB: 16.25 mg, 32.5 mg, 48.75 mg, 65 mg, 81.25 mg, 97.5 mg, 113.75 mg, 130 mg, 146.25 mg, 162.5 mg, 195 mg, 260 mg, 325 mg
Currently Unavailable in US
- [estimated availability unknown]
Special Note
- [strength clarification]
- Info: thyroid (porcine) contains liothyronine (T3) and levothyroxine (T4) in approx. 1:4 ratio; 60-65 mg thyroid (porcine) contain 9 mcg T3 and 38 mcg T4
- [thyroid product equivalencies]
- Info: for product conversion purposes, 60-65 mg thyroid (porcine) = 100 mcg levothyroxine = 25 mcg liothyronine = 1 grain liotrix
hypothyroidism, congenital
- [<6 mo]
- Dose: 16.25-32.5 mg PO qd; Alt: 5.2-6.5 mg/kg/dose PO qd; Info: start full dose upon diagnosis
- [6-11 mo]
- Dose: 32.5-48.75 mg PO qd; Alt: 3.9-5.2 mg/kg/dose PO qd; Info: start full dose upon diagnosis
- [1-5 yo]
- Dose: 48.75-65 mg PO qd; Alt: 3.25-3.9 mg/kg/dose PO qd
- [6-12 yo]
- Dose: 65-97.5 mg PO qd; Alt: 2.6-3.25 mg/kg/dose PO qd
- [>12 yo]
- Dose: 97.5-195 mg PO qd; Alt: 1.3-1.95 mg/kg/dose PO qd
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]