Gilenya

Adult Dosing .

Dosage forms:  CAP: 0.25 mg, 0.5 mg

multiple sclerosis, relapsing forms

[0.5 mg PO qd]

Info: for pts w/ clinically isolated syndrome, relapsing-remitting dz, and active secondary progressive dz

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined, caution advised

Peds Dosing .

Dosage forms:  CAP: 0.25 mg, 0.5 mg

multiple sclerosis, relapsing forms

[10 yo and older, <40 kg]

Dose: 0.25 mg PO qd; Info: for pts w/ clinically isolated syndrome, relapsing-remitting dz, and active secondary progressive dz

[10 yo and older, >40 kg]

Dose: 0.5 mg PO qd; Info: for pts w/ clinically isolated syndrome, relapsing-remitting dz, and active secondary progressive dz

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined, caution advised