Select a medication above to begin.
Qsymia
phentermine hydrochloride/ topiramate
Adult Dosing .
Dosage forms: CAP: 3.75 mg IR/23 mg ER, 7.5 mg IR/46 mg ER, 11.25 mg IR/69 mg ER, 15 mg IR/92 mg ER
Restricted Distribution in US
- [1-888-998-4887 or www.QsymiaREMS.com for more info]
weight management, chronic
- [7.5 mg/46 mg or 15 mg/92 mg PO qam]
- Start: 3.75 mg/23 mg PO qam x14 days, then incr. to 7.5 mg/46 mg PO qam; Max: 15 mg/92 mg/day; Info: for obese pts or overweight pts w/ wt-related comorbidity; if wt loss <3% after 12wk on 7.5 mg/46 mg dose, incr. to 11.25 mg/69 mg PO qam x14 days, then 15 mg/92 mg PO qam; D/C if wt loss <5% after 12wk on 15 mg/92 mg dose; taper 15 mg/92 mg dose to 15 mg/92 mg PO qod for at least 1wk to D/C
renal dosing
- [see below]
- CrCl <50: max 7.5 mg/46 mg/day
- HD/PD: avoid use
hepatic dosing
- [see below]
- Child-Pugh Class B: max 7.5 mg/46 mg/day; Child-Pugh Class C: not defined, caution advised
Peds Dosing .
- Dosage forms: CAP: 3.75 mg IR/23 mg ER, 7.5 mg IR/46 mg ER, 11.25 mg IR/69 mg ER, 15 mg IR/92 mg ER
Restricted Distribution in US
- [1-888-998-4887 or www.QsymiaREMS.com for more info]
weight management, chronic
- [12 yo and older]
- Dose: 7.5 mg/46 mg or 15 mg/92 mg PO qam; Start: 3.75 mg/23 mg PO qam x14 days, then incr. to 7.5 mg/46 mg PO qam; Max: 15 mg/92 mg/day; Info: for obese pts; if BMI change <3% after 12wk on 7.5 mg/46 mg dose, incr. to 11.25 mg/69 mg PO qam x14 days, then 15 mg/92 mg PO qam; D/C if BMI change <5% after 12wk on 15 mg/92 mg dose; if wt loss >2 lb/wk, consider dose reduction; taper 15 mg/92 mg dose to 15 mg/92 mg PO qod for at least 1wk to D/C
renal dosing
- [see below]
- CrCl <50: max 7.5 mg/46 mg/day
- HD/PD: avoid use
hepatic dosing
- [see below]
- Child-Pugh Class B: max 7.5 mg/46 mg/day; Child-Pugh Class C: not defined, caution advised