Breo Ellipta

Adult Dosing .

Dosage forms:  DPI: 100 mcg/25mcg per blister, 200 mcg/25mcg per blister

COPD, maintenance tx

[1 puff (100 mcg/25 mcg per blister) inhaled qd]

Info: search 'GOLD' for epocrates COPD decision tools

asthma, maintenance tx

[1 puff (100 mcg/25 mcg or 200 mcg/25 mcg per blister) inhaled qd]

Start: varies by dz severity and current asthma tx; Max: 200 mcg/25 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[see below]

mild impairment: no adjustment; moderate-severe impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  DPI: 50 mcg/25 mcg per blister, 100 mcg/25mcg per blister

asthma, maintenance tx

[5-11 yo]

Dose: 1 puff (50 mcg/25 mcg per blister) inhaled qd; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[12-17 yo]

Dose: 1 puff (100 mcg/25 mcg per blister) inhaled qd; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[not defined]

hepatic impairment: consider adult hepatic dosing for guidance