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Trintellix
vortioxetine
Black Box Warnings .
Suicidality
antidepressants incr. suicidality risk in peds and young adult pts in short-term studies; monitor closely for clinical worsening and suicidality; advise families and caregivers of need for close observation and communication w/ prescriber; not approved for peds pts
Adult Dosing .
Dosage forms: TAB: 5 mg, 10 mg, 20 mg
Brand Name Changed in US
- [previously Brintellix]
major depressive disorder
- [20 mg PO qd]
- Start: 10 mg PO qd; Info: may decr. to 5 mg PO qd if not tolerated; max 10 mg/day in CYP2D6 poor metabolizers; if receiving 15-20 mg/day, decr. dose to 10 mg/day x7 days to D/C
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.