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levomilnacipran
generic
Black Box Warnings .
Suicidality
antidepressants incr. suicidality risk in peds and young adult pts in short-term studies; monitor closely for clinical worsening and suicidality; advise families and caregivers of need for close observation and communication w/ prescriber; not approved for peds pts
Adult Dosing .
Dosage forms: ER CAP: 20 mg, 40 mg, 80 mg, 120 mg
major depressive disorder
- [40-120 mg PO qd]
- Start: 20 mg PO qd x2 days, then 40 mg PO qd; Max: 120 mg/day; Info: may incr. dose by 40 mg/day no more frequently than q2 days; taper dose gradually to D/C; do not open cap
renal dosing
- [adjust dose amount]
- CrCl 30-59: max 80 mg/day; CrCl 15-29: max 40 mg/day; ESRD: avoid use
- HD/PD: not defined
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.