Entyvio

Adult Dosing .

Dosage forms:  INJ (pen): 108 mg per injection; INJ (pre-filled syringe): 108 mg per 0.68 mL; INJ (vial): various

ulcerative colitis, moderate-severe

[IV route]

Dose: 300 mg IV q8wk; Start: 300 mg IV x1 at wk 0, 2, 6, then 300 mg IV q8wk; Info: may switch from IV to SC dosing at or after wk 6, give 1st SC dose at next scheduled IV dose; D/C if no response by wk 14

[SC route]

Dose: 108 mg SC q2wk; Start: 300 mg IV x1 at wk 0, 2, then 108 mg SC q2wk starting at wk 6; Info: if switching from IV to SC dosing after wk 6, give 1st SC dose at next scheduled IV dose; D/C if no response by wk 14

Crohn dz, moderate-severe

[IV route]

Dose: 300 mg IV q8wk; Start: 300 mg IV x1 at wk 0, 2, 6, then 300 mg IV q8wk; Info: may switch from IV to SC dosing at or after wk 6, give 1st SC dose at next scheduled IV dose; D/C if no response by wk 14

[SC route]

Dose: 108 mg SC q2wk; Start: 300 mg IV x1 at wk 0, 2, then 108 mg SC q2wk starting at wk 6; Info: if switching from IV to SC dosing after wk 6, give 1st SC dose at next scheduled IV dose; D/C if no response by wk 14

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.