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Ofev
nintedanib
Adult Dosing .
Dosage forms: CAP: 100 mg, 150 mg
idiopathic pulmonary fibrosis
- [150 mg PO q12h]
- Max: 300 mg/day; Info: see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap
chronic fibrosing interstitial lung dz
- [150 mg PO q12h]
- Max: 300 mg/day; Info: for pts w/ progressive phenotype; see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap
systemic sclerosis-assoc. interstitial lung dz
- [150 mg PO q12h]
- Max: 300 mg/day; Info: see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap
renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
hepatic dosing
- [see below]
- Child-Pugh Class A: 100 mg q12h; Child-Pugh Class B or C: avoid use
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.