Gardasil 9

Adult Dosing .

Dosage forms:  INJ

HPV-related cancer, dysplastic lesion, and genital wart prevention

[18-45 yo]

Dose: 0.5 mL IM x1 at mo 0, mo 1-2, and mo 6 for 3 total doses; Info: give to pts 27-45 yo based on shared clinical decision-making; repeat dose if <4wk between 1st and 2nd dose, <12wk between 2nd and 3rd dose, or <5mo between 1st and 3rd dose; search 'immunization' for epocrates Adult Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

HPV-related cancer, dysplastic lesion, and genital wart prevention

[9-14 yo, immunocompetent pts]

Dose: 0.5 mL IM x1 at mo 0 and mo 6-12 for 2 total doses; Info: give a 3rd dose at least 4mo after 2nd dose if 2nd dose given <5mo after 1st dose; start series at 9 yo if sexual abuse or assault hx; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[9-14 yo, immunocompromised pts]

Dose: 0.5 mL IM x1 at mo 0, mo 1-2, and mo 6 for 3 total doses; Info: repeat dose if <4wk between 1st and 2nd dose, <12wk between 2nd and 3rd dose, or <5mo between 1st and 3rd dose; start series at 9 yo if sexual abuse or assault hx; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[15-17 yo]

Dose: 0.5 mL IM x1 at mo 0, mo 1-2, and mo 6 for 3 total doses; Info: repeat dose if <4wk between 1st and 2nd dose, <12wk between 2nd and 3rd dose, or <5mo between 1st and 3rd dose; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]