Toujeo

Adult Dosing .

Dosage forms:  INJ (SoloStar U-300 pen): 300 units per mL (1.5 mL); INJ (Max SoloStar U-300 pen): 300 units per mL (3 mL)

Special Note

[formulation clarification]

Info: Max SoloStar U-300 pen for pts requiring at least 20 units/day

[strength clarification]

Info: SoloStar U-300 pen delivers dose in 1 unit increments; Max SoloStar U-300 pen delivers dose in 2 unit increments

[additional info]

Info: search Insulin Product Comparisons for comparison of onset, peak, duration, dosage form, and mixing compatibility

diabetes mellitus, type 1

[individualize dose SC qd]

Start: approx. 33-50% of total daily insulin requirement; Info: usual total daily insulin requirement 0.4-1 units/kg/day (basal + prandial); may adjust dose no more frequently than q3-4 days; use w/ rapid-acting or short-acting insulin; dose adjustment may be needed during pregnancy and/or immed. postpartum; onset 6h, no true peak, duration 24-36h (long-acting basal insulin)

diabetes mellitus, type 2

[individualize dose SC qd]

Start: 0.2 units/kg/dose SC qd; Info: may adjust dose no more frequently than q3-4 days; dose adjustment may be needed during pregnancy and/or immed. postpartum; onset 6h, no true peak, duration 24-36h (long-acting basal insulin)

renal dosing

[see below]

renal impairment: consider decr. usual start dose

HD/PD: consider decr. usual start dose; no supplement

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  INJ (SoloStar U-300 pen): 300 units per mL (1.5 mL); INJ (Max SoloStar U-300 pen): 300 units per mL (3 mL)

Special Note

[formulation clarification]

Info: Max SoloStar U-300 pen for pts requiring at least 20 units/day

[strength clarification]

Info: SoloStar U-300 pen delivers dose in 1 unit increments; Max SoloStar U-300 pen delivers dose in 2 unit increments

[additional info]

Info: search Insulin Product Comparisons for comparison of onset, peak, duration, dosage form, and mixing compatibility

diabetes mellitus, type 1

[6 yo and older]

Dose: individualize dose SC qd; Start: approx. 33-50% of total daily insulin requirement; Info: usual total daily insulin requirement 0.4-1 units/kg/day (basal + prandial); adolescents may require higher doses; may adjust dose no more frequently than q3-4 days; use w/ rapid-acting or short-acting insulin; onset 6h, no true peak, duration 24-36h (long-acting basal insulin)

diabetes mellitus, type 2

[6 yo and older]

Dose: individualize dose SC qd; Start: 0.2 units/kg/dose SC qd; Info: may adjust dose no more frequently than q3-4 days; onset 6h, no true peak, duration 24-36h (long-acting basal insulin)

renal dosing

[see below]

renal impairment: consider decr. usual start dose

HD/PD: consider decr. usual start dose; no supplement

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised