Cosentyx

Adult Dosing .

Dosage forms:  INJ (Sensoready pen, SC): 150 mg per injection; INJ (UnoReady pen, SC): 300 mg per injection; INJ (pre-filled syringe, SC): 75 mg per 0.5 mL, 150 mg per mL, 300 mg per 2 mL; INJ (IV): various

psoriasis, mod-severe plaque

[300 mg SC q4wk]

Start: 300 mg SC qwk x5wk; Info: may consider 150 mg/dose in pts w/ less severe dz and wt <90 kg

psoriatic arthritis

[SC route]

Dose: 150 mg SC q4wk; Info: may load 150 mg SC qwk x5wk; consider incr. dose to 300 mg SC q4wk if active dz persists; use plaque psoriasis dosing for pts w/ coexisting dz

[IV route]

Dose: 1.75 mg/kg/dose IV q4wk; Max: 300 mg/maint. dose; Info: may load 6 mg/kg/dose IV x1

ankylosing spondylitis

[SC route]

Dose: 150 mg SC q4wk; Info: may load 150 mg SC qwk x5wk; consider incr. dose to 300 mg SC q4wk if active dz persists

[IV route]

Dose: 1.75 mg/kg/dose IV q4wk; Max: 300 mg/maint. dose; Info: may load 6 mg/kg/dose IV x1

axial spondyloarthritis, non-radiographic

[SC route]

Dose: 150 mg SC q4wk; Info: may load 150 mg SC qwk x5wk

[IV route]

Dose: 1.75 mg/kg/dose IV q4wk; Max: 300 mg/maint. dose; Info: may load 6 mg/kg/dose IV x1

hidradenitis suppurativa, moderate-severe

[300 mg SC q4wk]

Start: 300 mg SC qwk x5wk; Info: consider incr. dose to 300 mg SC q2wk if inadequate response

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ (Sensoready pen): 150 mg per injection; INJ (pre-filled syringe): 75 mg per 0.5 mL, 150 mg per mL

psoriasis, mod-severe plaque

[6 yo and older, <50 kg]

Dose: 75 mg SC q4wk; Start: 75 mg SC qwk x5wk

[6 yo and older, >50 kg]

Dose: 150 mg SC q4wk; Start: 150 mg SC qwk x5wk

psoriatic arthritis

[2 yo and older, 15-49 kg]

Dose: 75 mg SC q4wk; Start: 75 mg SC qwk x5wk

[2 yo and older, >50 kg]

Dose: 150 mg SC q4wk; Start: 150 mg SC qwk x5wk

enthesitis-related arthritis

[4 yo and older, 15-49 kg]

Dose: 75 mg SC q4wk; Start: 75 mg SC qwk x5wk

[4 yo and older, >50 kg]

Dose: 150 mg SC q4wk; Start: 150 mg SC qwk x5wk

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]