Select a medication above to begin.
Anthrasil
anthrax immune globulin (human)
Black Box Warnings .
Thrombosis
risk factors incl. pts >65 yo, prolonged immobilization, hypercoagulable conditions, venous or arterial thrombosis hx, estrogen use, indwelling central vascular catheter, hyperviscosity, and cardiovascular dz risk; thrombosis may occur in pts w/o risk factors; ensure adequate hydration before admin; give at lowest infusion rate practicable in pts at risk; monitor for s/sx thrombosis and assess blood viscosity in pts w/ hyperviscosity risk
Blood Glucose Test Interference
maltose contained in IG product may give falsely high blood glucose levels w/ some point-of-care blood glucose testing systems incl. those based on GDH-PQQ or glucose-dye-oxidoreductase methods, resulting in inappropriate insulin admin. and life-threatening hypoglycemia; to avoid maltose interference perform blood glucose measurement w/ glucose-specific method for monitor and test strips
Adult Dosing .
Dosage forms: INJ
Restricted Distribution in US
- [distributed directly to CDC]
inhalational anthrax
- [420-840 units IV x1]
- Info: give w/ antibiotics; may repeat dose if severe dz
renal dosing
- [see below]
- renal impairment: not defined, caution advised; Info: use minimum infusion rate practicable
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Restricted Distribution in US
- [distributed directly to CDC]
inhalational anthrax
- [<5 kg]
- Dose: 60 units IV x1; Info: give w/ antibiotics; may repeat dose if severe dz
- [5-9 kg]
- Dose: 60-120 units IV x1; Info: give w/ antibiotics; may repeat dose if severe dz
- [10-17 kg]
- Dose: 120-240 units IV x1; Info: give w/ antibiotics; may repeat dose if severe dz
- [18-24 kg]
- Dose: 180-360 units IV x1; Info: give w/ antibiotics; may repeat dose if severe dz
- [25-34 kg]
- Dose: 240-480 units IV x1; Info: give w/ antibiotics; may repeat dose if severe dz
- [35-49 kg]
- Dose: 300-600 units IV x1; Info: give w/ antibiotics; may repeat dose if severe dz
- [50-59 kg]
- Dose: 360-720 units IV x1; Info: give w/ antibiotics; may repeat dose if severe dz
- [60 kg and up]
- Dose: 420-840 units IV x1; Info: give w/ antibiotics; may repeat dose if severe dz
renal dosing
- [see below]
- renal impairment: not defined, caution advised; Info: use minimum infusion rate practicable
- HD/PD: not defined
hepatic dosing
- [not defined]