Namzaric

Adult Dosing .

Dosage forms:  CAP: 7 mg ER/10 mg IR, 14 mg ER/10 mg IR, 21 mg ER/10 mg IR, 28 mg ER/10 mg IR; convenience pack

Special Note

[convenience pack components]

Info: starting 4-wk pack contains 7 mg ER/10 mg IR cap x7 and 14 mg ER/10 mg IR cap x7 and 21 mg ER/10 mg IR cap x7 and 28 mg ER/10 mg IR cap x7

Alzheimer dz, moderate-severe dementia

[conversion from donepezil monotherapy]

Dose: 28 mg ER/10 mg IR PO qhs; Start: 4-wk convenience pack; Max: 28 mg ER/10 mg IR per day; Info: for pts stable on donepezil 10 mg/day; may open cap, but do not crush/chew contents

[conversion from memantine plus donepezil]

Dose: 28 mg ER/10 mg IR PO qhs; Max: 28 mg ER/10 mg IR per day; Info: for pts stable on memantine 20 mg/day IR or memantine 28 mg/day ER and donepezil 10 mg/day; may open cap, but do not crush/chew contents

renal dosing

[adjust dose amount]

CrCl 5-29: max 14 mg ER/10 mg IR per day; CrCl <5: not defined

HD/PD: not defined

hepatic dosing

[see below]

mild-moderate impairment: no adjustment; severe impairment: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.