Bridion

Adult Dosing .

Dosage forms:  INJ

nondepolarizing neuromuscular blockade reversal

[rocuronium or vecuronium moderate blockade]

Dose: 2 mg/kg/dose IV x1; Info: for pts undergoing surgery w/ spontaneous recovery reaching reappearance of 2nd twitch to train-of-four; use ABW to calculate dose; see pkg insert for neuromuscular blocking agent readministration recommendations

[rocuronium or vecuronium deep blockade]

Dose: 4 mg/kg/dose IV x1; Info: for pts undergoing surgery w/ spontaneous twitch response recovery reaching 1-2 post-tetanic counts and no twitch response to train-of-four; use ABW to calculate dose; see pkg insert for neuromuscular blocking agent readministration recommendations

[rocuronium immediate reversal]

Dose: 16 mg/kg/dose IV x1; Info: for pts undergoing surgery requiring reversal after rocuronium 1.2 mg/kg/dose IV x1; use ABW to calculate dose; see pkg insert for neuromuscular blocking agent readministration recommendations

renal dosing

[see below]

CrCl <30: avoid use

HD/PD: avoid use

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

nondepolarizing neuromuscular blockade reversal

[rocuronium or vecuronium moderate blockade]

Dose: 2 mg/kg/dose IV x1; Info: for pts undergoing surgery w/ spontaneous recovery reaching reappearance of 2nd twitch to train-of-four; use ABW to calculate dose; see pkg insert for neuromuscular blocking agent readministration recommendations

[rocuronium or vecuronium deep blockade]

Dose: 4 mg/kg/dose IV x1; Info: for pts undergoing surgery w/ spontaneous twitch response recovery reaching 1-2 post-tetanic counts and no twitch response to train-of-four; use ABW to calculate dose; see pkg insert for neuromuscular blocking agent readministration recommendations

renal dosing

[see below]

CrCl <30: avoid use

HD/PD: avoid use

hepatic dosing

[not defined]