Select a medication above to begin.
promethazine/ dextromethorphan
generic
Black Box Warnings .
Respiratory Depression
contraindicated in pts <2 yo due to cases of resp. depression, some fatal, at wide-range of wt-based doses; in pts 2 yo and older, use w/ caution at lowest effective dose, avoid combo w/ other resp. depressant drugs
Adult Dosing .
Dosage forms: SOL: 6.25 mg/15 mg per 5 mL
upper respiratory sx
- [5 mL PO q4-6h prn]
- Max: 30 mL/24h
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised
Peds Dosing .
- Dosage forms: SOL: 6.25 mg/15 mg per 5 mL
upper respiratory sx
- [2-5 yo]
- Dose: 1.25-2.5 mL PO q4-6h prn; Max: 10 mL/24h
- [6-11 yo]
- Dose: 2.5-5 mL PO q4-6h prn; Max: 20 mL/24h
- [12 yo and older]
- Dose: 5 mL PO q4-6h prn; Max: 30 mL/24h
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised