fluticasone propionate inhaled

Adult Dosing .

Dosage forms:  DPI: 50 mcg per blister, 100 mcg per blister, 250 mcg per blister; MDI: 44 mcg per actuation, 110 mcg per actuation, 220 mcg per actuation

asthma, maintenance tx

[DPI form]

Dose: 1-4 puffs (50 mcg, 100 mcg, 250 mcg per blister) inhaled bid; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 2000 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[MDI form]

Dose: 2-4 puffs (44 mcg, 110 mcg, or 220 mcg per actuation) inhaled bid; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 1760 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

eosinophilic esophagitis (off-label)

[MDI form]

Dose: 440-880 mcg swallowed bid x8-12wk, then taper to lowest effective dose; Info: avoid food/drink x30-60min after each dose

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised

Peds Dosing .

Dosage forms:  DPI: 50 mcg per blister, 100 mcg per blister, 250 mcg per blister; MDI: 44 mcg per actuation, 110 mcg per actuation, 220 mcg per actuation

asthma, maintenance tx

[DPI form, 4-11 yo]

Dose: 1 puff (50 mcg or 100 mcg per blister) inhaled bid; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 200 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[DPI form, 12 yo and older]

Dose: 1-4 puffs (50 mcg, 100 mcg, or 250 mcg per blister) inhaled bid; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 2000 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[MDI form, 4-11 yo]

Dose: 2 puffs (44 mcg per actuation) inhaled bid; Max: 176 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

[MDI form, 12 yo and older]

Dose: 2-4 puffs (44 mcg, 110 mcg, or 220 mcg per actuation) inhaled bid; Start: varies by dz severity and current asthma tx, may incr. dose after 2wk; Max: 1760 mcg/day; Info: taper to lowest effective dose; search 'asthma' for epocrates Asthma Long-Term Mgmt NIH/NHLBI decision tools

eosinophilic esophagitis (off-label)

[MDI form, children/adolescents]

Dose: 88-440 mcg swallowed bid-qid x8-12wk, then taper to lowest effective dose; Info: avoid food/drink x30-60min after each dose

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised