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Trulance
plecanatide
Black Box Warnings .
Pediatric Risk
contraindicated in pts <6 yo; deaths occurred due to dehydration w/in 24h in nonclinical studies in young juvenile mice after admin. of a single oral dose; avoid use in pts 6 yo to less than 18 yo; safety and efficacy not established in pts <18 yo
Adult Dosing .
Dosage forms: TAB: 3 mg
chronic idiopathic constipation
- [3 mg PO qd]
IBS, constipation-predominant
- [3 mg PO qd]
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.