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Fosamax
alendronate
Adult Dosing .
Dosage forms: TAB: 70 mg
Dosage Forms Discontinued in US
- [5 mg, 10 mg, 35 mg, 40 mg tab, 70 mg per 75 mL oral solution not avail. as brand; see generic]
osteoporosis tx, postmenopausal
- [70 mg PO qwk]
- Info: give w/ water, 30min before first food/drink/med, avoid lying down x30min; calcium and vitamin D supplementation recommended if inadequate dietary intake; reassess need for tx in 3-5y; may consider drug holiday if stable after tx x5y (low-mod risk pt); optimal holiday duration up to 5y; if drug holiday initiated, reassess need for tx q2-4y and consider resuming tx in pts w/ fracture or significant BMD loss
osteoporosis, male
- [70 mg PO qwk]
- Info: give w/ water, 30min before first food/drink/med, avoid lying down x30min; calcium and vitamin D supplementation recommended if inadequate dietary intake; periodically reassess need for tx; consider D/C after 3-5y in low-risk pts
renal dosing
- [see below]
- CrCl <35: avoid use
- HD/PD: not defined
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.