Select a medication above to begin.
Siliq
brodalumab
Black Box Warnings .
Appropriate Use
restricted distribution program (Siliq REMS) due to risk of suicidality; prescribers, pharmacies must be certified and pts must sign a patient-prescriber agreement form; 1-855-511-6135 or www.siliqems.com for more information
Suicidality
incr. risk of suicidality in pts w/ hx of depression and/or suicidal ideation; weigh risk vs. benefit; advise pts and caregivers to seek medical attention for suicidality, new onset or worsening depression, anxiety, or other mood changes
Adult Dosing .
Dosage forms: INJ (pre-filled syringe): 210 mg per 1.5 mL
Restricted Distribution in US
- [1-855-511-6135 or www.siliqrems.com for more information]
psoriasis, mod-severe plaque
- [210 mg SC q2wk]
- Start: 210 mg SC x1 on wk 0, 1, 2, then q2wk; Info: consider D/C if inadequate response after 12-16 wk
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.