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Bicillin C-R
penicillin G benzathine/ penicillin G procaine
Black Box Warnings .
Not for IV Use
do not admin. IV or admix w/ other IV solution; cardioresp. arrest and death assoc. w/ inadvertent IV admin.
Prescribing Information
prescribers should be familiar w/ complete prescribing information before use
Adult Dosing .
Dosage forms: INJ (1.2 million units pre-filled syringe): 600,000 units/600,000 units per 2 mL
Special Note
- [strength clarification]
- Info: doses expressed as total penicillin G amt
infections, Group A Strep.
- [2.4 million units IM x1]
- Alt: 1.2 million units IM q48h x2 doses
pneumococcal pneumonia, mod. severe
- [1.2 million units IM q2-3 days]
- Info: give until afebrile x48h
renal dosing
- [see below]
- renal impairment: not defined, caution advised
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ (1.2 million units pre-filled syringe): 600,000 units/600,000 units per 2 mL, 900,000 units/300,000 units per 2 mL
Special Note
- [strength clarification]
- Info: doses expressed as total penicillin G amt
infections, Group A Strep.
- [<14 kg]
- Dose: 600,000 units (1 mL) IM x1; Alt: 300,000 units IM q48h x2 doses; Info: use 600,000 units/600,000 units syringe
- [14-27 kg]
- Dose: 0.9-1.2 million units (1.5-2 mL) IM x1; Alt: 0.45-0.6 million units (0.75-1 mL) IM q48h x2 doses; Info: use 600,000 units/600,000 units syringe
- [>27 kg]
- Dose: 2.4 million units (4 mL) IM x1; Alt: 1.2 million units (2 mL) IM q48h x2 doses; Info: use 600,000 units/600,000 units syringe
- [non weight-based dosing]
- Dose: 1.2 million units (2 mL) IM x1; Info: use 900,000 units/300,000 units syringe
pneumococcal pneumonia, mod-severe
- [600,000 units/600,000 units syringe]
- Dose: 600,000 units (1 mL) IM q2-3 days; Info: give until afebrile x48h
- [900,000 units/300,000 units syringe]
- Dose: 1.2 million units (2 mL) IM q2-3 days; Info: give until afebrile x48h
renal dosing
- [see below]
- renal impairment: not defined, caution advised
- HD/PD: not defined
hepatic dosing
- [not defined]