Calquence

Adult Dosing .

Dosage forms:  TAB: 100 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments; consider holding tx x3-7 days before and after surgery if bleeding risk

mantle cell lymphoma

[previously untreated dz]

Dose: 100 mg PO q12h; Info: for pts ineligible for autologous HSCT; part of multi-drug chemo regimen; do not cut/crush/chew tab

[previously treated dz]

Dose: 100 mg PO q12h; Info: do not cut/crush/chew tab

CLL/SLL

[100 mg PO q12h]

Info: for previously untreated dz, may use w/ obinutuzumab starting 28 days after tx start; do not cut/crush/chew tab

renal dosing

[see below]

eGFR >30: no adjustment; eGFR <30: not defined

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class C: avoid use

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.