Kenalog-10

Adult Dosing .

Dosage forms:  INJ: 10 mg per mL

gout, acute

[small joints]

Dose: 2.5-5 mg intra-articularly x1; Max: 10 mg/site up to 80 mg/total dose; Info: use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

[large joints]

Dose: 5-15 mg intra-articularly x1; Max: 40 mg/site up to 80 mg/total dose; Info: use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

rheumatoid arthritis

[small joints]

Dose: 2.5-5 mg intra-articularly x1; Max: 10 mg/site up to 80 mg/total dose; Info: use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

[large joints]

Dose: 5-15 mg intra-articularly x1; Max: 40 mg/site up to 80 mg/total dose; Info: use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

osteoarthritis

[small joints]

Dose: 2.5-5 mg intra-articularly x1; Max: 10 mg/site up to 80 mg/total dose; Info: use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

[large joints]

Dose: 5-15 mg intra-articularly x1; Max: 40 mg/site up to 80 mg/total dose; Info: use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

joint/joint structure inflammation

[small joints]

Dose: 2.5-5 mg intra-articularly x1; Max: 10 mg/site up to 80 mg/total dose; Info: for acute bursitis, acute nonspecific tenosynovitis, epicondylitis, and synovitis; use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

[large joints]

Dose: 5-15 mg intra-articularly x1; Max: 40 mg/site up to 80 mg/total dose; Info: for acute bursitis, acute nonspecific tenosynovitis, epicondylitis, and synovitis; use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

alopecia areata

[individualize dose intralesionally x1]

Info: may inject multiple sites at least 1 cm apart; may repeat qwk or less frequently

discoid lupus erythematosus

[individualize dose intralesionally x1]

Info: may inject multiple sites at least 1 cm apart; may repeat qwk or less frequently

keloids

[individualize dose intralesionally x1]

Info: may inject multiple sites at least 1 cm apart; may repeat qwk or less frequently

inflammatory lesions, localized hypertrophic infiltrated

[individualize dose intralesionally x1]

Info: for granuloma annulare, lichen planus, lichen simplex chronicus (neurodermatitis), and psoriatic plaques; may inject multiple sites at least 1 cm apart; may repeat qwk or less frequently

necrobiosis lipoidica diabeticorum

[individualize dose intralesionally x1]

Info: may inject multiple sites at least 1 cm apart; may repeat qwk or less frequently

cystic tumor

[individualize dose intralesionally x1]

Info: for aponeurosis or tendon (ganglia); Info: may inject multiple sites at least 1 cm apart; may repeat qwk or less frequently

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ: 10 mg per mL

juvenile idiopathic arthritis

[small joints, 2 yo and older]

Dose: 2.5-5 mg intra-articularly x1; Max: 10 mg/site up to 80 mg/total dose; Info: use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

[large joints, 2 yo and older]

Dose: 5-15 mg intra-articularly x1; Max: 40 mg/site up to 80 mg/total dose; Info: use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

joint/joint structure inflammation

[small joints, 2 yo and older]

Dose: 2.5-5 mg intra-articularly x1; Max: 10 mg/site up to 80 mg/total dose; Info: for acute bursitis, acute nonspecific tenosynovitis, epicondylitis, and synovitis; use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

[large joints, 2 yo and older]

Dose: 5-15 mg intra-articularly x1; Max: 40 mg/site up to 80 mg/total dose; Info: for acute bursitis, acute nonspecific tenosynovitis, epicondylitis, and synovitis; use lowest effective dose, shortest effective tx duration; taper dose gradually to D/C if long-term use

inflammatory lesions, localized hypertrophic infiltrated

[12 yo and older]

Dose: individualize dose intralesionally x1; Max: 1 mg/site up to 30 mg/total dose; Info: for granuloma annulare, lichen planus, lichen simplex chronicus (neurodermatitis), and psoriatic plaques; may inject multiple sites at least 1 cm apart; may repeat qwk or less frequently

renal dosing

[see below]

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

hepatic dosing

[not defined]