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Perseris
risperidone
Black Box Warnings .
Dementia-Related Psychosis
not approved for dementia-related psychosis; incr. mortality risk in elderly pts on antipsychotic tx for dementia-related psychosis; most deaths due to cardiovascular or infectious events
Adult Dosing .
Dosage forms: INJ (pre-filled syringe): 90 mg, 120 mg
schizophrenia
- [90 mg or 120 mg SC qmo]
- Start: after establishing tolerability w/ oral risperidone; Max: 1 dose/mo; Info: give 1st SC dose day after last PO dose; risperidone 90 mg SC qmo corresponds to 3 mg/day PO, risperidone 120 mg SC qmo corresponds to 4 mg/day PO; periodically reassess need for tx; D/C if ANC <1000; consider D/C if unexplained decr. in WBC
renal dosing
- [see below]
- renal impairment: 90 mg SC qmo if tolerating at least 3 mg/day PO
- HD/PD: not defined
hepatic dosing
- [see below]
- hepatic impairment: 90 mg SC qmo if tolerating at least 3 mg/day PO
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.