Takhzyro (lanadelumab-flyo)

Adult Dosing .

Dosage forms:  INJ (pre-filled syringe): 150 mg per mL, 300 mg per 2 mL; INJ (vial): 300 mg per 2 mL

Restricted Distribution in US

[1-866-888-0660 or www.takhzyro.com for more info]

Special Note

[formulation clarification]

Info: nonproprietary name = lanadelumab-flyo

hereditary angioedema prophylaxis, routine

[300 mg SC q2wk]

Info: may give q4wk if attack free >6mo

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ (pre-filled syringe): 150 mg per mL, 300 mg per 2 mL; INJ (vial): 300 mg per 2 mL

Restricted Distribution in US

[1-866-888-0660 or www.takhzyro.com for more info]

Special Note

[formulation clarification]

Info: nonproprietary name = lanadelumab-flyo

hereditary angioedema prophylaxis, routine

[2-5 yo]

Dose: 150 mg SC q4wk

[6-11 yo]

Dose: 150 mg SC q2wk; Info: may give q4wk if attack free >6mo

[12 yo and older]

Dose: 300 mg SC q2wk; Info: may give q4wk if attack free >6mo

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[not defined]