artesunate

Adult Dosing .

Dosage forms:  INJ

malaria, severe

[2.4 mg/kg/dose IV q12h x3 doses, then 2.4 mg/kg/dose IV q24h for up to 7 days]

Info: cont. tx until parasitemia <1%, then give course of appropriate PO tx regimen; if P. vivax or P. ovale infection, follow PO tx regimen w/ primaquine or tafenoquine to avoid relapse; refer to CDC guidelines

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

malaria, severe

[2.4 mg/kg/dose IV q12h x3 doses, then 2.4 mg/kg/dose IV q24h for up to 7 days]

Info: cont. tx until parasitemia <1%, then give course of appropriate PO tx regimen; if P. vivax or P. ovale infection, follow PO tx regimen w/ primaquine or tafenoquine to avoid relapse; refer to CDC guidelines

renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

hepatic dosing

[no adjustment]