Sogroya (somapacitan-beco)

Adult Dosing .

Dosage forms:  INJ (pen): 5 mg per 1.5 mL, 10 mg per 1.5 mL, 15 mg per 1.5 mL

Special Note

[formulation clarification]

Info: nonproprietary name = somapacitan-beco

[strength clarification]

Info: 5 mg per 1.5 mL pen delivers 0.025-2 mg/dose in 0.025 mg increments; 10 mg per 1.5 mL pen delivers 0.05-4 mg/dose in 0.05 mg increments; 15 mg per 1.5 mL pen delivers 0.1-8 mg/dose in 0.1 mg increments

growth hormone deficiency

[individualize dose SC qwk]

Start: 1.5 mg SC qwk, may incr. by 0.5-1.5 mg/dose q2-4wk; Max: 8 mg/wk; Info: adjust dose based on IGF-1 levels and sx; start 1 mg SC qwk and titrate in smaller increments in pts 65 yo and older

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class B: start 1 mg qwk and titrate in smaller increments, max 4 mg/wk; Child-Pugh Class C: avoid use

Peds Dosing .

Dosage forms:  INJ (pen): 5 mg per 1.5 mL, 10 mg per 1.5 mL, 15 mg per 1.5 mL

Special Note

[formulation clarification]

Info: nonproprietary name = somapacitan-beco

[strength clarification]

Info: 5 mg per 1.5 mL pen delivers 0.025-2 mg/dose in 0.025 mg increments; 10 mg per 1.5 mL pen delivers 0.05-4 mg/dose in 0.05 mg increments; 15 mg per 1.5 mL pen delivers 0.1-8 mg/dose in 0.1 mg increments

growth hormone deficiency

[2.5 yo and older]

Dose: 0.16 mg/kg/dose SC qwk; Info: D/C when pt reaches satisfactory ht, epiphyses close, or no response

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class B or C: avoid use