Onureg

Adult Dosing .

Dosage forms:  TAB: 200 mg, 300 mg

Special Note

[formulation clarification]

Info: do not substitute for SC/IV azacitidine

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

AML

[300 mg PO qd on days 1-14 of 28-day cycle]

Info: for continued tx in pts who achieved complete remission (CR) or CR w/ incomplete hematologic recovery (CRi) after intensive induction chemo, and ineligible for intensive curative tx; do not cut/crush/chew tab

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined, caution advised

HD/PD: not defined

hepatic dosing

[see below]

bilirubin 1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.