lovastatin

Adult Dosing .

Dosage forms:  TAB: 10 mg, 20 mg, 40 mg

hypercholesterolemia

[20-80 mg PO qpm]

Max: 80 mg/day; Info: may adjust dose q4wk; give w/ food; search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

mixed dyslipidemia

[20-80 mg PO qpm]

Max: 80 mg/day; Info: may adjust dose q4wk; give w/ food; search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

cardiovascular event risk reduction

[20-80 mg PO qpm]

Max: 80 mg/day; Info: may adjust dose q4wk; give w/ food; search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

atherosclerotic cardiovascular dz

[20-80 mg PO qpm]

Max: 80 mg/day; Info: may adjust dose q4wk; give w/ food; search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined, caution advised if dose >20 mg/day

HD/PD: not defined

hepatic dosing

[see below]

active hepatic dz/unexplained elev. LFTs: contraindicated

Peds Dosing .

Dosage forms:  TAB: 10 mg, 20 mg, 40 mg

heterozygous familial hypercholesterolemia

[10-17 yo, males and postmenarchal females]

Dose: 10-40 mg PO qd; Start: 20 mg PO qpm, may incr. dose q4wk; Max: 40 mg/day; Info: may start 10 mg PO qpm in pts w/ <20% LDL reduction goal; give w/ food

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined, caution advised if dose >20 mg/day

HD/PD: not defined

hepatic dosing

[see below]

active hepatic dz/unexplained elev. LFTs: contraindicated