Select a medication above to begin.
fosinopril
generic
Black Box Warnings .
Fetal Toxicity
fetal/neonatal morbidity/mortality may occur when drugs that act directly on the renin-angiotensin system are used in pregnancy; D/C drug ASAP once pregnancy detected
Adult Dosing .
Dosage forms: TAB: 10 mg, 20 mg, 40 mg
HTN
- [10-40 mg PO qd]
- Start: 10 mg PO qd; Max: 80 mg/day
heart failure w/ reduced ejection fraction
- [40 mg PO qd]
- Start: 10 mg PO qd, may incr. dose q1-2wk; Max: 40 mg/day; Info: start 5 mg PO qd if pt diuresed
MI, acute (off-label)
- [10-20 mg PO qd]
nephropathy (off-label)
- [20 mg PO qd]
renal dosing
- [heart failure w/ reduced ejection fraction]
- moderate-severe impairment: start 5 mg qd
- HD/PD: no adjustment; no supplement
- [all other indications]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised
Peds Dosing .
- Dosage forms: TAB: 10 mg, 20 mg, 40 mg
HTN
- [6-16 yo, <50 kg (off-label)]
- Dose: 5-10 mg PO qd; Start: 0.1 mg/kg/dose PO qd up to 5 mg/day; Max: 40 mg/day
- [6-16 yo, >50 kg]
- Dose: 5-10 mg PO qd; Max: 40 mg/day
- [17 yo and older]
- Dose: 10-40 mg PO qd; Start: 10 mg PO qd; Max: 80 mg/day
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [see below]
- hepatic impairment: not defined, caution advised