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Verquvo
vericiguat
Black Box Warnings .
Embryo-Fetal Toxicity
contraindicated in pregnancy; exclude pregnancy in females of reproductive potential prior to tx start; use effective methods of contraception during tx and x1mo after D/C
Adult Dosing .
Dosage forms: TAB: 2.5 mg, 5 mg, 10 mg
heart failure w/ reduced ejection fraction, symptomatic
- [10 mg PO qd]
- Start: 2.5 mg PO qd, then double dose q2wk as tolerated; Info: for pts recently hospitalized for heart failure, or receiving outpatient IV diuretic tx; give w/ food
renal dosing
- [see below]
- eGFR >15: no adjustment; eGFR <15: not defined
- HD/PD: not defined
hepatic dosing
- [see below]
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.