St. John's wort (Hypericum perforatum)

Reported Uses

• NOTE: see Herb & Supplement Effectiveness Rating Definitions table
• acne [Insufficient Evidence]
• ADHD [Insufficient Evidence]
• anxiety [Insufficient Evidence]
• brain tumor [Insufficient Evidence]
• burning mouth syndrome [Possibly Ineffective]
• chronic fatigue syndrome [Insufficient Evidence]
• Crigler-Najjar syndrome type 2 [Insufficient Evidence]
• depression [Likely Effective]
• fibromyalgia [Insufficient Evidence]
• genital herpes [Insufficient Evidence]
• hepatitis C [Possibly Ineffective]
• herpes labialis (cold sores) [Insufficient Evidence]
• HIV/AIDS [Possibly Ineffective]
• IBS [Possibly Ineffective]
• mastitis [Insufficient Evidence]
• memory [Insufficient Evidence]
• menopausal sx [Possibly Effective]
• migraine prophylaxis [Insufficient Evidence]
• obsessive-compulsive disorder [Insufficient Evidence]
• osteoarthritis [Insufficient Evidence]
• peripheral neuropathy [Possibly Ineffective]
• plaque psoriasis [Insufficient Evidence]
• polycystic ovary syndrome [Insufficient Evidence]
• premenstrual syndrome [Insufficient Evidence]
• scleroderma [Insufficient Evidence]
• seasonal affective disorder [Insufficient Evidence]
• smoking cessation [Insufficient Evidence]
• social anxiety disorder [Possibly Ineffective]
• somatoform disorders [Possibly Effective]
• tinnitus [Insufficient Evidence]
• wound healing [Insufficient Evidence]