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strychnos
ashwagandha (Withania somnifera)
Reported Doses
Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies w/ variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely
Effectiveness Ratings
- [see Herb & Supplement Effectiveness Rating Definitions table]
aging
- [Insufficient Evidence]
- Dose: 600 mg PO qd
androgenic alopecia
- [Insufficient Evidence]
- Dose: apply 1-2 gtt serum topically qd; Info: product containing 5% root extract
anxiety
- [Possibly Effective]
- Dose: 300 mg PO bid; Alt: 500 mg PO qd
athletic performance
- [Insufficient Evidence]
- Dose: 500-1000 mg PO qd; Alt: 120-1250 mg/day PO divided qd-bid
bipolar disorder
- [Insufficient Evidence]
- Dose: 250 mg PO bid; Start: 250 mg PO qd x1wk
cerebellar ataxia
- [Insufficient Evidence]
- Dose: 500 mg PO tid
constipation
- [Insufficient Evidence]
- Dose: 300-500 mg PO qd; Info: product containing 45% extract in 1:1 ratio ashwagandha root:ambrette fruit
COPD
- [Insufficient Evidence]
- Dose: 250 mg PO bid; Info: used w/ conventional tx
COVID-19
- [Insufficient Evidence]
- Dose: 500-600 mg PO bid
depression
- [Insufficient Evidence]
- Dose: 500 mg PO qd
diabetes mellitus, type 2
- [Insufficient Evidence]
- Dose: 3 g PO qd
fatigue
- [Insufficient Evidence]
- Dose: 200 mg PO bid
fatigue, chemo-related
- [Insufficient Evidence]
- Dose: 2 g PO tid
generalized anxiety disorder
- [Possibly Effective]
- Dose: 0.3-1 g PO qd; Alt: 4 g PO tid; Info: used w/ or w/o standard tx
hypercholesterolemia
- [Insufficient Evidence]
- Dose: 3 g PO qd
hypothyroidism
- [Insufficient Evidence]
- Dose: 300 mg PO bid
insomnia
- [Possibly Effective]
- Dose:120-600 mg PO qd
male infertility
- [Insufficient Evidence]
- Dose: 5 g PO qd; Alt: 225 mg PO tid
menopausal sx
- [Insufficient Evidence]
- Dose: 300 mg PO bid
metabolic effects, antipsychotic-induced
- [Insufficient Evidence]
- Dose: 400 mg PO tid
obsessive-compulsive disorder
- [Insufficient Evidence]
- Dose: 120 mg PO qd; Start: 30 mg PO qd x4 days, then incr. by 30 mg/day q4 days; Info: used w/ selective-serotonin reuptake inhibitor
osteoarthritis
- [Insufficient Evidence]
- Dose: 900 mg PO tid
Parkinson dz
- [Insufficient Evidence]
- Dose: 14.5 g PO bid
psychological well-being
- [Insufficient Evidence]
- Dose: 350 mg PO bid
rheumatoid arthritis
- [Insufficient Evidence]
- Dose: 5 g PO bid
sexual dysfxn
- [Insufficient Evidence]
- Dose: 300 mg PO bid
smoking cessation
- [Insufficient Evidence]
- Dose: 100 mg PO qd
stress
- [Possibly Effective]
- Dose: 125-1000 mg PO qd; Alt: 300-500 mg PO bid
wrinkled skin
- [Insufficient Evidence]
- Dose: apply 8% lotion topically qd
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