By vgreene, 12 November, 2020 Use of Ivermectin Is Associated With Lower Mortality in Hospitalized Patients With Coronavirus Disease 2019 access Chest article
By vgreene, 12 November, 2020 Association of Treatment With Hydroxychloroquine or Azithromycin With In Hospital Mortality in Patients With COVID 19 in New York State full text JAMA article
By vgreene, 12 November, 2020 No significant difference in clinical status at 14 days adjusted OR 1 02 95 CI 0 73 1 42 no significant difference in death rate at 28 days adjust OR 1 07 95 CI 0 54 2 09
By vgreene, 12 November, 2020 Multicenter blinded RCT 479 hospitalized pts median age 57y w severe dz received HCQ 400 mg bid x1 day then 200 mg bid x4 days n 242 vs placebo n 237 median sx duration 5 days pts also received RDV 21 7 AZ 19 CS 18 4
By vgreene, 12 November, 2020 Study considerations terminated early due to low enrollment included pts w respiratory sx for up to 10 days f u limited to 28 days no eval for viral shedding inflammatory biomarkers effect of other tx
By vgreene, 12 November, 2020 KEY FINDINGS HCQ did not significantly improve clinical status at day 14 vs placebo
By vgreene, 12 November, 2020 Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID 19 A Randomized Clinical Trial ORCHID
