By vgreene, 28 September, 2016 Measure SCr & estimate CrCl at baseline to guide selection of regimen & 4-6wk after exposure for regimens using TDF/FTC, RAL, or DTG
By vgreene, 28 September, 2016 Perform rapid combined Ag/Ab HIV test (or Ab test, if Ag/Ab test unavailable)2-4 at baseline, then 4-6wk, 3mo, & 6mo;5 obtain HBV serology & HCV Ab at baseline & 6mo6,7 after any exposure
By vgreene, 28 September, 2016 Adults/Adolescents (incl pregnant women)<sup>10</sup> ≥13 yo w/ CrCl ≥60 mL/min
By vgreene, 28 September, 2016 ✓syphilis serology,13 chlamydia/gonorrhea NAAT,14 & pregnancy tests15 at baseline, then 4-6wk after sexual exposure & prescribe appropriate prophylaxis16
By vgreene, 28 September, 2016 Counsel on effective risk redux behaviors;11 consider PrEP at conclusion of nPEP if pt at risk for frequent exposure12
By vgreene, 28 September, 2016 If source is known to have drug resistance or if nPEP candidate has contraindications to any preferred or alternative ARVs, seek consultation w/ HIV specialist10
By vgreene, 28 September, 2016 Prescribe entire 28-day course of nPEP;8 counsel on expected adverse drug reactions & prescribe prophylactic antiemetics9
By vgreene, 28 September, 2016 Measure AST/ALT at baseline, 4-6wk after exposure for regimens using TDF/FTC, RAL, or DTG, & throughout duration of tx as necessary for all regimens
By vgreene, 28 September, 2016 Measure SCr & estimate CrCl at baseline to guide selection of regimen & 4-6wk after exposure for regimens using TDF/FTC, RAL, or DTG
