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Journal Article Synopsis

Am J Gastroenterol

ACG releases new guideline for eosinophilic esophagitis management

January 28, 2025

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The guideline, developed by the American College of Gastroenterology (ACG), provides evidence-based recommendations for the diagnosis and management of eosinophilic esophagitis (EoE). Recommendations are based on a comprehensive review of current literature and expert consensus.

Key recommendations

  • Proton pump inhibitors should be used as a treatment option.
  • Topical steroids are recommended for managing EoE.
  • Empiric diet elimination can be an effective treatment strategy.
  • Biologic therapy is recommended for certain patients.
  • Esophageal dilation may be necessary for some patients.
  • Feeding therapy should be used adjunctively in children with food aversion or feeding dysfunction.
  • Clinical, endoscopic, and histologic assessments should be conducted to evaluate treatment response and maintain therapy.
  • Both the inflammatory and fibrostenotic aspects of EoE should be assessed and controlled during patient evaluation and follow-up.

Source:

Dellon ES, et al. (2025, January 1). Am J Gastroenterol. ACG Clinical Guideline: Diagnosis and Management of Eosinophilic Esophagitis. https://pubmed.ncbi.nlm.nih.gov/39745304/

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