CDC: New cluster of tecovirimat-resistant mpox cases detected in 5 states

Tecovirimat, the primary treatment for orthopoxvirus infections like smallpox and mpox, can become ineffective due to viral mutations. A new cluster of tecovirimat-resistant mpox cases was found in five U.S. states among individuals without prior tecovirimat treatment. Routine genetic surveillance is essential to detect and monitor resistance. To prevent the spread of resistant mpox virus, tecovirimat should be used according to CDC’s Investigational New Drug protocol. Tap for details ...