Ann Neurol
Neurologic manifestations of long COVID disproportionately affect younger and middle-aged adults
Study Design: This cross-sectional study evaluated neurologic manifestations of post-acute sequelae of SARS-CoV-2 infection (Neuro-PASC) in 1,300 patients at a Neuro-COVID clinic from May 2020 to March 2023. Participants were categorized into younger (18-44 years), middle-aged (45-64 years), and older (65+ years) groups to assess differences in symptoms and cognitive function.
Results: Younger and middle-aged adults accounted for 71% of post-hospitalization and 90.5% of non-hospitalized Neuro-PASC patients. Notably, younger patients reported higher levels of fatigue, sleep disturbances, and cognitive dysfunction compared with older adults, who exhibited more frequent abnormal neurologic findings but lower symptom burden.
Impact on Clinical Practice: These findings highlight the significant neurologic impacts of Neuro-PASC on younger and middle-aged adults, emphasizing the need for targeted interventions to address long-term quality of life and cognitive function challenges.
Source:
Choudhury NA, et al. (2024, November 22). Ann Neurol. Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle-Age Adults. https://pubmed.ncbi.nlm.nih.gov/39575583/