JAMA Intern Med
Patients more likely to fill PrEP script when prescribed by ID specialist
Primary care practitioners (PCPs) are the main prescribers of new PrEP and serve as a crucial entry point for patients. Patient adherence to PrEP varies by clinician specialty, likely due to the different populations they serve. Future research should focus on interventions that support adherence and provide education.
- A cross-sectional study analyzed pharmacy claims data from 2015 to 2019 for new PrEP prescriptions matched with clinician data from the U.S. National Plan and Provider Enumeration System. Analysis included 37,003 patients (88% male; 77% ages 25-54 years). Prescriptions were given by PCPs (67%), ID specialists (10%), and other specialists (24%).
- Reversal was defined as not picking up the initial PrEP prescription and abandonment as not picking it up within 1 year after reversal. Reversal rates were 18% for patients of PCPs and ID specialists, and 25% for other specialists. Abandonment rates were 12% for patients of PCPs and ID specialists, and 20% for other specialists.
- Logistic regression models showed that patients prescribed PrEP by ID specialists had 10% lower odds of reversal and 12% lower odds of abandonment compared with that of PCPs. Patients prescribed PrEP by other specialists had 33% higher odds of reversal and 54% higher odds of abandonment.
Source:
Bakre S, et al. (2024, August 19). JAMA Intern Med. Clinician Specialty and HIV PrEP Prescription Reversals and Abandonments. https://pubmed.ncbi.nlm.nih.gov/39158923/