Sci Adv

Python tooth-inspired device could double strength of rotator cuff repairs

July 10, 2024

More than 600,000 rotator cuff repairs are performed annually in the U.S. However, successfully reattaching tendon to bone remains a significant clinical challenge and high failure rates plague the procedure. Over time, the sutures that stitch tendons onto shoulder bones tend to slice through the tendon in places where stress is highest. To address this issue, researchers drew inspiration from an unlikely source – the python, which uses its teeth to grasp victims without tearing them.

Key results

Stavros Thomopoulos, PhD, of Columbia University, and his team hypothesized that 3D printed biomimetic devices modeled after python teeth can be used to strengthen tendon-bone attachments. They designed their device to mimic the curvature and spacing of python teeth. The design was tested on shoulder joints from human cadavers. The curved “teeth” enhanced mechanical strength to the repair, exhibiting an average increase in strength of 83% relative to matched controls without the device.

The biomimetic device has limitations, including the use of a solid base that could hinder tendon-bone integration. Future versions should explore bioabsorbable materials and a porous structure for better healing and localized drug delivery.

Source:

Kurtaliaj I, et al. (2024, June 28). Sci Adv. Python tooth-inspired fixation device for enhanced rotator cuff repair. https://pubmed.ncbi.nlm.nih.gov/38941456/