JAMA Opthalmol

Smartphone app could make for faster, more accurate measurement of ocular proptosis

September 25, 2023

A smartphone scanning app provided more accurate measurements of eyeball protrusion than the Hertel exophthalmometer and could allow for inexpensive monitoring of exophthalmos, a symptom of Graves’ disease, vascular conditions, and some cancers.

• Researchers conducted a cross-sectional study that included 39 participants, 23 with exophthalmos and 16 without.
• Three methods of measurement were used to examine the participants’ degree of exophthalmos: the Hertel exophthalmometer, the existing reference standard; smartphone exophthalmometry; and a professional high-resolution three-dimensional scanner.
• Accuracy and precision between the smartphone and Hertel exophthalmometer showed an intraclass correlation coefficient (ICC) of 0.89 (95% CI 0.80-0.94) and 0.93 (95% CI 0.83-0.97) for the high-resolution scanner.
• Interoperator agreement was highest for the high-resolution scanner (ICC 0.99, 95% CI 0.98-0.99), followed by the smartphone app (ICC 0.95, 95% CI 0.92-0.97) and the Hertel exophthalmometer (ICC 0.91, 95% CI 0.85-0.95).
• Test-retest reliability was similarly high for the smartphone, the Hertel exophthalmomenter, and the high-resolution scanner (ICC 0.93, 0.92, and 0.95, respectively).

Source:

Popov T. (2023, Sep 21). JAMA Ophthalmol. Using Smartphone Exophthalmometry to Measure Eyeball Protrusion. https://pubmed.ncbi.nlm.nih.gov/37733348/