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Top viewed medical news articles: August 2025

August 4, 2025

Hospital-wide switch to lactated Ringer’s fails to reduce death or readmission

(N Engl J Med)—It's been unclear whether lactated Ringer’s offers a clinical advantage over normal saline for routine IV fluid use ... Read more

Hormone therapy: A double-edged sword for younger women?

(NIH)—NIH study finds estrogen-only therapy lowers breast cancer risk, while combined therapy raises it, especially among individuals without prior hysterectomy or oophorectomy ... Read more

More evidence for esketamine monotherapy in treatment-resistant depression

(JAMA Psychiatry)—This is the first large randomized trial to test esketamine nasal spray as monotherapy in TRD, addressing a key evidence gap ... Read more

Deprescribing benzodiazepines and sedative hypnotics: Pharmacist-led interventions may help

(BMJ)—Long-term use of benzodiazepines and related sedative hypnotics is common despite known risks, prompting evaluation of deprescribing strategies ... Read more

Medical groups sue HHS over vaccine policy shake-up

(AAP)—Lawsuit claims RFK Jr. sidelined science and violated federal law in reshaping COVID-19 vaccine guidance ... Read more

Are all types of intermittent fasting created equal?

(BMJ)—Intermittent fasting strategies show similar weight loss to continuous energy restriction, with alternate day fasting offering modest additional benefit ... Read more

Vaped nicotine is better for cessation than nicotine replacement therapy in socioeconomically disadvantaged smokers

(Ann Intern Med)—Although vaporized nicotine products are known to be more effective than nicotine replacement therapy in general populations, their effectiveness among low socioeconomic groups has been largely unknown ... Read more