Zebra of the Week: Lichen sclerosus

Lichen sclerosus (LS) affects the skin leading to scarring around the genital and anal areas. It mainly affects the skin around the vagina, anus, and tip of the penis. Symptoms can include white lesions or plaques, pain during urination, itching, and pain during intercourse. Some people have no symptoms, while others may experience pruritus (sometimes severe), discomfort, or blistering. Although the underlying cause of LS isn't known, it's thought to relate to an autoimmune process. Diagnosis is based on symptoms and clinical exam; a skin biopsy may confirm the diagnosis.