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cannabis (Cannabis sativa)
Reported Doses
Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies w/ variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely
Special Note
- [formulation clarification]
- Info: medical cannabis typically involves unprocessed plant parts or extracts; active compounds are cannabinoids and may contain psychoactive delta-9-tetrahydrocannabinol (THC) and nonpsychoactive cannabidiol (CBD) components; for sole CBD constituent info see 'cannabidiol (CBD herbal extract)'; for FDA-approved Rx products see 'dronabinol' (oral synthetic THC) or 'cannabidiol (CBD)' (oral purified CBD); all other preparations are not FDA-approved
Effectiveness Ratings
- [see Herb & Supplement Effectiveness Rating Definitions table]
alcohol use disorder
- [Insufficient Evidence]
- Dose: 1-3 g (1% THC and 24% CBD) cannabis flower via inhalation qd
blepharospasm
- [Insufficient Evidence]
- Dose: 1-10 gtt (1.2-12 mg THC) cannabis extract PO qhs; Start: 1 gtt cannabis extract PO qhs, then may titrate to optimal dose; Max: 10 gtt/day; Info: extract containing 3.2% THC
chronic pain
- [Insufficient Evidence]
- Dose: 0.5-1 mg THC via inhalation x1
Crohn dz
- [Insufficient Evidence (PO route)]
- Dose: 2-40 mg THC and 8-160 mg CBD PO bid; Start: 2 mg THC and 8 mg CBD PO bid, then may titrate to optimal dose; Max: 80 mg/day THC and 320 mg/day CBD; Info: cannabis oil containing 4% THC and 16% CBD; given before meals; used w/ standard tx
- [Insufficient Evidence (inhalation route)]
- Dose: 115 mg THC via inhalation bid
fibromyalgia
- [Insufficient Evidence]
- Dose: 22.4 mg THC and <1 mg CBD via inhalation x1
glaucoma
- [Insufficient Evidence]
- Dose: 18 mg THC via inhalation x1; Info: 900 mg cigarette stdzd to 2% THC
HTN
- [Insufficient Evidence]
- Dose: average 21.1 mg THC and 21.3 mg CBD PO qd; Info: cannabis oil containing 1-10% THC and 2-20% CBD
multiple sclerosis
- [Possibly Effective]
- Dose: 2.5 mg THC and 1.25 mg CBD PO bid, then incr. by 5 mg/day THC and 2.5 mg CBD q3 days for up to 12 days; Alt: 25-30 mg THC and 8-18 mg CBD PO qd; 10-15 mg/day THC PO divided bid
nausea/vomiting, chemo-induced
- [Insufficient Evidence]
- Dose: 2.5 mg THC and 2.5 mg CBD PO tid on days 1-5 of chemo cycle
neuropathic pain
- [Possibly Effective]
- Dose: 1.6-96 mg THC via inhalation qd
Parkinson dz
- [Insufficient Evidence]
- Dose: 0.5 g cannabis via inhalation x1
post-traumatic stress disorder
- [Insufficient Evidence]
- Dose: 1.8 g cannabis flower via inhalation qd; Info: cannabis flower containing either 12% THC, 11% CBD, or a combination of 7.9% THC and 8.1% CBD
ulcerative colitis
- [Insufficient Evidence]
- Dose: 80 mg THC via inhalation bid; Info: used w/ standard tx
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